Ultimate Cheesy Chicken Spaghetti Casserole: Your Go-To Comfort Food Recipe
Prepare to fall in love with Cheesy Chicken Spaghetti, a truly comforting and incredibly flavorful weeknight meal that’s so delicious, even the most discerning eaters will ask for seconds. This easy-to-make chicken casserole comes together with minimal fuss, taking around 35 minutes from start to finish for a warm, bubbly, and satisfying dish that the whole family will adore. It’s the perfect blend of creamy pasta, tender chicken, and a rich, cheesy sauce, making it an instant classic in any home.
Why This Cheesy Chicken Spaghetti Recipe is a Must-Try
This Cheesy Chicken Spaghetti casserole isn’t just another pasta dish; it’s a culinary masterpiece that simplifies mealtime without sacrificing taste. Its brilliance lies in the harmonious blend of simple, readily available ingredients. We combine tender spaghetti noodles with succulent chicken and a luxurious three-cheese mixture – cream cheese for unparalleled creaminess, sharp cheddar for a bold flavor kick, and mozzarella for that irresistible, gooey stretch. Beyond the core components, a medley of flavorful elements like diced tomatoes with green chiles (Rotel), aromatic onions, and bell peppers infuse every bite with depth and zest.
What truly sets this recipe apart is its incredible versatility and convenience. It’s an easy mash-up of ingredients you probably already have stocked in your pantry and fridge, making it a fantastic last-minute dinner solution. Furthermore, this chicken spaghetti casserole is an excellent candidate for meal prepping; it freezes beautifully, allowing you to prepare it ahead of time and have a delicious, homemade meal ready to bake whenever hunger strikes. While we certainly cherish a hearty plate of classic spaghetti and meatballs, this cheesy chicken version offers a delightful twist that brings new excitement to your dinner table, proving that comfort food can be both familiar and wonderfully innovative.
RELATED: If you love creamy chicken pasta, you might also enjoy this delicious recipe for – Creamy Chicken Alfredo.
Essential Ingredients for Cheesy Chicken Spaghetti
Crafting this delicious casserole requires a straightforward list of ingredients, most of which are likely staples in your kitchen. This recipe focuses on fresh chicken, classic pasta, and a rich, creamy cheese sauce base. For exact measurements, a comprehensive list, and detailed instructions, refer to the printable recipe card located at the end of this blog post. Gather these key components to create a truly memorable meal:
Ingredient Spotlight & Smart Substitutions
Let’s dive deeper into the ingredients and explore ways to customize this fantastic recipe to your liking or what you have on hand:
NOODLES – This recipe specifically calls for thin spaghetti noodles. Their delicate texture allows them to absorb the rich, creamy sauce beautifully, ensuring every strand is coated in flavor. However, feel free to experiment with other pasta shapes! Regular spaghetti, linguine, fettuccine, penne, or even elbow macaroni could work wonders, though they might alter the final texture and cooking time slightly. The key is to slightly undercook the pasta initially, as it will continue to cook and soak up the delicious juices in the oven.
CHICKEN – We recommend 2 1/2 lbs of boneless, skinless chicken breasts, diced into 1/2-inch cubes for even cooking and distribution throughout the casserole. For ultimate convenience, this recipe truly shines when made with leftover rotisserie chicken or any pre-cooked shredded chicken you might have. If using cooked chicken, you’ll need about 4-5 cups shredded. Simply skip the initial step of cooking the chicken and add your pre-cooked chicken directly to the sauce mixture. This makes the recipe even quicker!
CHEESES – The star of this dish is its irresistible three-cheese blend: cream cheese for a smooth, tangy base, sharp cheddar for a robust, savory punch, and mozzarella for its classic melty, stretchy goodness. You can use freshly shredded cheese for the best melt and flavor, or opt for pre-shredded bagged cheese for ease. Don’t be afraid to experiment with other cheeses like Colby Jack, Monterey Jack, or even a hint of smoked Gouda for a different flavor profile.
ROTEL – Rotel is a popular canned product containing diced tomatoes and green chiles, adding a subtle tang and a mild kick to the sauce. If you prefer to avoid canned goods or adjust the spice level, you can substitute with a can of plain diced tomatoes and add 1-2 finely diced fresh jalapeños (deseeded for less heat) or a small can of diced green chiles. For a completely fresh approach, use 1 cup of finely diced fresh tomatoes and 1/4 cup of finely diced fresh green chiles or serrano peppers.
VEGETABLES – Diced yellow onion and green bell pepper form the aromatic foundation of this sauce, providing essential flavor and texture. Feel free to incorporate other vegetables like finely diced celery, mushrooms, or even a handful of frozen peas or corn (added during the final combining step) to boost the nutritional content and add color.
SEASONING – Poultry seasoning is a great all-around blend for chicken. You can also use a mixture of onion powder, garlic powder, paprika, dried oregano, salt, and black pepper to taste. Don’t forget to season the chicken before cooking it for maximum flavor!
How to Master Cheesy Chicken Spaghetti: Step-by-Step
These step-by-step photos and detailed instructions are designed to help you visualize each stage of making this delightful recipe. For a convenient printable version, complete with precise measurements and instructions, simply Jump to Recipe at the bottom of this post.
- Cook the Pasta: Begin by cooking your thin spaghetti according to the package directions. It’s crucial to drain it a minute or two before it reaches the al dente stage. This slight undercooking ensures the pasta will continue to absorb the flavorful sauce in the oven, preventing it from becoming mushy. Once drained, return the cooked spaghetti to its pot for later combining.
- Prepare the Chicken: While your pasta water is heating, preheat your oven to 350°F (175°C). Dice the boneless, skinless chicken breasts into uniform 1/2-inch cubes. In a large 12-inch skillet, melt the olive oil and butter over medium-high heat. Add the diced chicken along with the poultry seasoning. Cook for approximately 7 minutes, stirring occasionally, until the chicken is cooked through and lightly golden. Remove the cooked chicken from the skillet and set it aside, leaving any flavorful drippings in the pan. This fond will add incredible depth to your sauce.
- Sauté Aromatics and Make the Roux: Into the same skillet (with the chicken drippings), add the diced onion and green pepper. Sauté for about 5 minutes until they soften and become fragrant. Stir in the minced garlic and cook for another 30 seconds to 1 minute, being careful not to burn it. Sprinkle the all-purpose flour over the sautéed vegetables and mix well, stirring constantly for 1-2 minutes to cook out the raw flour taste. This creates a roux, which will thicken your sauce.
- Build the Creamy Sauce: Gradually add the chicken stock, 1/2 cup at a time, to the roux in the skillet, whisking vigorously after each addition. Allow the mixture to thicken before adding more stock. Continue this process until all the chicken stock has been incorporated and you have a smooth, thickened sauce. Next, stir in the can of Rotel (undrained) and the room temperature cream cheese. Continue to mix until the cream cheese has fully melted and the sauce is smooth and creamy.
- Combine and Bake: In the still-warm pasta pot, combine the cooked spaghetti, the reserved cooked chicken, and the creamy Rotel cheese sauce. Stir everything together thoroughly until the pasta and chicken are evenly coated. Transfer this luscious mixture into a casserole dish. Spread the mixture evenly, then generously top with the shredded mozzarella and sharp cheddar cheeses. Bake for 15 minutes, or until the cheese is beautifully melted and bubbly, but not overly browned. You want it warm, gooey, and irresistible.
- Garnish and Serve: For a fresh burst of color and flavor, garnish your hot chicken spaghetti casserole with a sprinkle of fresh chopped parsley and a dusting of grated Parmesan cheese, if desired. Serve immediately and enjoy!
Frequently Asked Questions & Expert Tips for Success
Absolutely! This cheesy chicken spaghetti dish freezes exceptionally well, making it perfect for future meals. To freeze, allow the prepared and cooked chicken spaghetti (before the final oven melt of the cheeses) to cool completely. Transfer it into an airtight, freezer-safe container or a disposable aluminum pan. It can be frozen for up to 3 months. If you use a freezer-to-oven safe casserole dish, there’s no need to thaw before baking; simply bake at 350°F (175°C) until hot and bubbly, adding extra time (around 45-60 minutes) to account for it being frozen. If using a non-freezer-safe dish, allow it to come to room temperature first, then bake as directed until piping hot and the cheese is melted.
Store any leftover chicken spaghetti in an airtight container or a sealed Ziploc bag in the refrigerator. It will keep fresh for 2-3 days. Reheat gently in the microwave or oven until warmed through. You may need to add a splash of milk or chicken broth if it seems a little dry upon reheating.
Yes, definitely! While Rotel offers convenience and a consistent flavor, you can certainly switch out the canned ingredients for fresh ones if that’s your preference. Use about 1 cup of finely diced fresh Roma tomatoes and 1-2 finely diced fresh green chiles or jalapeños (remove seeds for less heat). Sauté them along with the onions and bell peppers to soften them up before adding the flour for the roux.
Yes, this casserole is a fantastic make-ahead meal! You can prepare the entire dish, combining the pasta, chicken, and sauce, and transfer it to the casserole dish. Cover it tightly with plastic wrap and refrigerate for up to 24 hours. When ready to bake, remove it from the fridge 30 minutes before baking, top with cheese, and bake as directed, potentially adding an extra 5-10 minutes to the baking time since it will be chilled.
If your sauce appears too thick after incorporating the chicken stock and cream cheese, gradually whisk in a little more chicken stock (1-2 tablespoons at a time) until it reaches your desired consistency. If the sauce is too thin, you can let it simmer gently for a few more minutes to reduce and thicken, or create a small slurry with a teaspoon of cornstarch mixed with cold water and whisk it into the simmering sauce. Cook for a minute or two until thickened.
Delicious Serving Suggestions for Cheesy Chicken Spaghetti
Cheesy chicken spaghetti is a wonderfully hearty and filling meal that can certainly stand on its own, especially after a long day. However, it pairs exquisitely with a few simple sides that complement its rich flavors and creamy texture. Enhance your dining experience with a side of warm, crusty homemade Italian bread or classic garlic bread, perfect for soaking up every last bit of the delicious sauce. A crisp, fresh side salad with a light vinaigrette also provides a welcome contrast, cutting through the richness with its bright, refreshing flavors.
For an extra touch of freshness and visual appeal, always consider topping your spaghetti with some vibrant, freshly chopped parsley and an additional sprinkle of grated Parmesan cheese just before serving. This casserole is particularly inviting during the cooler months when you’re craving a meal that warms you from the inside out, offering true comfort food bliss. But let’s be honest, how can you ever go wrong with a fantastic pasta dish? It’s a crowd-pleaser that’s absolutely delicious and satisfying any time of the year!
Explore More Comforting Casserole Recipes
If you love the ease and comfort of a good casserole, you’re in luck! Here are some more delightful casserole recipes that are perfect for family dinners and gatherings:
- Hearty Taco Casserole
- Southwest Ground Beef Casserole
- Classic John Wayne Casserole
- Flavorful Mexican Chicken Casserole
- Comforting Chicken and Dumpling Casserole
- Macaroni and Cheese Casserole with Ham and Peas
- Classic Chicken Tetrazzini
- Indulgent Million Dollar Spaghetti
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Cheesy Chicken Spaghetti Casserole
IMPORTANT – There are often Frequently Asked Questions within the blog post that you may find helpful. Simply scroll back up to read them!
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Ingredients
- 16 oz thin spaghetti
- 2 Tbsp olive oil
- 2 Tbsp butter
- 2 ½ lb boneless skinless chicken breasts
- 1 Tbsp poultry seasoning
- 1 yellow onion small, diced
- 1 green pepper diced
- 2 tsp minced garlic
- 2 Tbsp all purpose flour
- 1 ½ cup chicken stock
- 10 oz rotel with chiles
- 4 oz cream cheese at room temperature
- 1 cup shredded mozzarella
- 1 cup shredded sharp cheddar
Equipment You’ll Need
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13×9 inch baking dish
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Large skillet (12-inch recommended)
Before You Begin: Important Notes
- Store leftovers in an airtight container in the refrigerator for 3-4 days.
- For the best melty texture and flavor, we recommend using freshly shredded cheese. However, pre-shredded bagged cheese works perfectly for convenience.
- Ensure cream cheese is at room temperature for a smoother, lump-free sauce.
- Undercooking the pasta slightly before baking is key; it will absorb the sauce and finish cooking in the oven, preventing a mushy texture.
Instructions
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Cook thin spaghetti according to package instructions, but drain it 1-2 minutes before it’s al dente. This prevents overcooking in the oven. Return the cooked spaghetti to the pot.
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Preheat your oven to 350°F (175°C). Dice chicken breasts into 1/2-inch cubes. Heat olive oil and butter in a large 12-inch skillet over medium-high heat. Add the diced chicken and poultry seasoning. Cook for about 7 minutes, stirring occasionally, until the chicken is cooked through. Remove the chicken from the skillet and set aside, leaving any liquid in the pan.
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Add the diced onion and green pepper to the same skillet. Sauté for approximately 5 minutes until softened. Stir in the minced garlic and cook for an additional 30 seconds to 1 minute. Sprinkle the all-purpose flour over the vegetables and stir continuously for 1-2 minutes to cook out the raw flour taste and thicken the mixture into a roux.
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Gradually add the chicken stock, about 1/2 cup at a time, whisking well after each addition and allowing the sauce to thicken before adding more. Once all the chicken stock is incorporated, stir in the can of Rotel (undrained) and the room temperature cream cheese. Mix thoroughly until the cream cheese has fully melted and the sauce is smooth and creamy.
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In the still-warm pasta pot, combine the cooked spaghetti, the reserved chicken, and the creamy sauce. Stir well to ensure everything is evenly coated. Transfer the mixture to a casserole dish. Evenly top with the shredded mozzarella and sharp cheddar cheeses. Bake for 15 minutes, or until the cheese is melted and bubbly.
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For garnish and an extra touch of flavor, top with fresh chopped parsley and a sprinkle of Parmesan cheese, if desired. Serve immediately and enjoy your comforting Cheesy Chicken Spaghetti!
Nutrition Information
The recipes on this blog are tested with a conventional gas oven and gas stovetop. It’s important to note that some ovens, especially as they age, can cook and bake inconsistently. Using an inexpensive oven thermometer can assure you that your oven is truly heating to the proper temperature. If you use a toaster oven or countertop oven, please keep in mind that they may not distribute heat the same as a conventional full sized oven and you may need to adjust your cooking/baking times. In the case of recipes made with a pressure cooker, air fryer, slow cooker, or other appliance, a link to the appliances we use is listed within each respective recipe. For baking recipes where measurements are given by weight, please note that results may not be the same if cups are used instead, and we can’t guarantee success with that method.